*Arsenal FC 3-0 SSC Napoli
| 18.04.2019 | SSC Napoli | 0-1 | Arsenal FC | |
| 11.04.2019 | Arsenal FC | 2-0 | SSC Napoli | |
SL Benfica 4-4 Eintracht Frankfurt *
| 18.04.2019 | Eintracht Frankfurt | 2-0 | SL Benfica | |
| 11.04.2019 | SL Benfica | 4-2 | Eintracht Frankfurt | |
Slavia Praha 3-5 Chelsea FC *
| 18.04.2019 | Chelsea FC | 4-3 | Slavia Praha | |
| 11.04.2019 | Slavia Praha | 0-1 | Chelsea FC | |
Villarreal CF 1-5 Valencia CF *
| 18.04.2019 | Valencia CF | 2-0 | Villarreal CF | |
| 11.04.2019 | Villarreal CF | 1-3 | Valencia CF | |