AFC Ajax 2-6 Eintracht Frankfurt *
| 13.03.2025 | Eintracht Frankfurt | 4-1 | AFC Ajax | |
| 06.03.2025 | AFC Ajax | 1-2 | Eintracht Frankfurt | |
AS Roma 3-4 Athletic Bilbao *
| 13.03.2025 | Athletic Bilbao | 3-1 | AS Roma | |
| 06.03.2025 | AS Roma | 2-1 | Athletic Bilbao | |
Fenerbahçe SK 3-3 Rangers FC *
| 13.03.2025 | Rangers FC | 0-2/p.3-2 | Fenerbahçe SK | |
| 06.03.2025 | Fenerbahçe SK | 1-3 | Rangers FC | |
Viktoria Plzen 2-3 Lazio *
| 13.03.2025 | Lazio | 1-1 | Viktoria Plzen | |
| 06.03.2025 | Viktoria Plzen | 1-2 | Lazio | |
*FK Bodo/Glimt 4-2 Olympiakos Pireus
| 13.03.2025 | Olympiakos Pireus | 2-1 | FK Bodo/Glimt | |
| 06.03.2025 | FK Bodo/Glimt | 3-0 | Olympiakos Pireus | |
Real Sociedad 2-5 Manchester United *
| 13.03.2025 | Manchester United | 4-1 | Real Sociedad | |
| 06.03.2025 | Real Sociedad | 1-1 | Manchester United | |
AZ Alkmaar 2-3 Tottenham *
| 13.03.2025 | Tottenham | 3-1 | AZ Alkmaar | |
| 06.03.2025 | AZ Alkmaar | 1-0 | Tottenham | |