FC Basel 3-4 Middlesbrough
| 06.04.2006 | Middlesbrough | 4-1 | FC Basel | |
| 30.03.2006 | FC Basel | 2-0 | Middlesbrough | |
Levski Sofia 2-4 Schalke 04
| 06.04.2006 | Schalke 04 | 1-1 | Levski Sofia | |
| 30.03.2006 | Levski Sofia | 1-3 | Schalke 04 | |
Rapid Bucuresti 1-1 Steaua Bucuresti
| 06.04.2006 | Steaua Bucuresti | 0-0 | Rapid Bucuresti | |
| 30.03.2006 | Rapid Bucuresti | 1-1 | Steaua Bucuresti | |
Sevilla FC 5-2 Zenit
| 06.04.2006 | Zenit | 1-1 | Sevilla FC | |
| 30.03.2006 | Sevilla FC | 4-1 | Zenit | |