*Werder Bremen 4-3 AFC Ajax
| 22.02.2007 | AFC Ajax | 3-1 | Werder Bremen | |
| 14.02.2007 | Werder Bremen | 3-0 | AFC Ajax | |
*Shakhtar Donetsk 2-1 AS Nancy-Lorraine
| 22.02.2007 | AS Nancy-Lorraine | 0-1 | Shakhtar Donetsk | |
| 14.02.2007 | Shakhtar Donetsk | 1-1 | AS Nancy-Lorraine | |
Fenerbahçe SK 5-5 AZ Alkmaar *
| 22.02.2007 | AZ Alkmaar | 2-2 | Fenerbahçe SK | |
| 14.02.2007 | Fenerbahçe SK | 3-3 | AZ Alkmaar | |
*Bayer Leverkusen 3-2 Blackburn Rovers
| 22.02.2007 | Blackburn Rovers | 0-0 | Bayer Leverkusen | |
| 14.02.2007 | Bayer Leverkusen | 3-2 | Blackburn Rovers | |
Girondins Bordeaux 0-1 CA Osasuna *
| 22.02.2007 | CA Osasuna | 1-0 AET | Girondins Bordeaux | |
| 14.02.2007 | Girondins Bordeaux | 0-0 | CA Osasuna | |
Spartak Moscow 2-3 Celta de Vigo *
| 22.02.2007 | Celta de Vigo | 2-1 | Spartak Moscow | |
| 15.02.2007 | Spartak Moscow | 1-1 | Celta de Vigo | |
*SL Benfica 3-1 Dinamo Bucuresti
| 22.02.2007 | Dinamo Bucuresti | 1-2 | SL Benfica | |
| 14.02.2007 | SL Benfica | 1-0 | Dinamo Bucuresti | |
Feyenoord 0-6 Tottenham *
| 22.02.2007 | Tottenham | 3-0 W.O. | Feyenoord | |
| 14.02.2007 | Feyenoord | 0-3 W.O. | Tottenham | |
Livorno 1-4 RCD Espanyol *
| 22.02.2007 | RCD Espanyol | 2-0 | Livorno | |
| 14.02.2007 | Livorno | 1-2 | RCD Espanyol | |
CSKA Moscow 0-1 Maccabi Haifa *
| 22.02.2007 | Maccabi Haifa | 1-0 | CSKA Moscow | |
| 14.02.2007 | CSKA Moscow | 0-0 | Maccabi Haifa | |
Zulte Waregem 1-4 Newcastle United *
| 22.02.2007 | Newcastle United | 1-0 | Zulte Waregem | |
| 15.02.2007 | Zulte Waregem | 1-3 | Newcastle United | |
AEK Athens 0-4 Paris St. Germain *
| 22.02.2007 | Paris St. Germain | 2-0 | AEK Athens | |
| 14.02.2007 | AEK Athens | 0-2 | Paris St. Germain | |
Hapoel Tel Aviv 2-5 Rangers FC *
| 22.02.2007 | Rangers FC | 4-0 | Hapoel Tel Aviv | |
| 14.02.2007 | Hapoel Tel Aviv | 2-1 | Rangers FC | |
*RC Lens 3-1 Panathinaikos
| 22.02.2007 | Panathinaikos | 0-0 | RC Lens | |
| 15.02.2007 | RC Lens | 3-1 | Panathinaikos | |
Steaua Bucuresti 0-3 Sevilla FC *
| 22.02.2007 | Sevilla FC | 1-0 | Steaua Bucuresti | |
| 15.02.2007 | Steaua Bucuresti | 0-2 | Sevilla FC | |