*Young Boys Youth 3-3 AIK Youth
| 02.11.2022 | AIK Youth | 0-3/p.8-9 | Young Boys Youth | |
| 26.10.2022 | Young Boys Youth | 0-3 | AIK Youth | |
Apolonia Fier Youth 1-6 Hajduk Split U19 *
| 02.11.2022 | Hajduk Split U19 | 3-1 | Apolonia Fier Youth | |
| 26.10.2022 | Apolonia Fier Youth | 0-3 | Hajduk Split U19 | |
*Panathinaikos Youth 6-3 AS Trenčín Youth
| 02.11.2022 | AS Trenčín Youth | 3-4 | Panathinaikos Youth | |
| 26.10.2022 | Panathinaikos Youth | 2-0 | AS Trenčín Youth | |
*AZ Alkmaar Youth 3-3 Crvena Zvezda Youth
| 01.11.2022 | Crvena Zvezda Youth | 1-1/p.3-4 | AZ Alkmaar Youth | |
| 25.10.2022 | AZ Alkmaar Youth | 2-2 | Crvena Zvezda Youth | |
*Hibernian Youth 3-1 FC Nantes Youth
| 02.11.2022 | FC Nantes Youth | 1-2 | Hibernian Youth | |
| 26.10.2022 | Hibernian Youth | 1-0 | FC Nantes Youth | |
Galatasaray Youth 2-6 Rukh Lviv Youth *
| 02.11.2022 | Rukh Lviv Youth | 3-1 | Galatasaray Youth | |
| 26.10.2022 | Galatasaray Youth | 1-3 | Rukh Lviv Youth | |
FC Ashdod Youth 1-2 MTK Budapest U19 *
| 02.11.2022 | MTK Budapest U19 | 0-1 | FC Ashdod Youth | |
| 26.10.2022 | FC Ashdod Youth | 0-2 | MTK Budapest U19 | |
Coleraine FC Youth 1-10 Racing Genk Youth *
| 02.11.2022 | Racing Genk Youth | 6-1 | Coleraine FC Youth | |
| 26.10.2022 | Coleraine FC Youth | 0-4 | Racing Genk Youth | |