*Chelsea (W) 3-1 Atlético Madrid (W)
| 10.03.2021 | Atlético Madrid (W) | 1-1 | Chelsea (W) | |
| 03.03.2021 | Chelsea (W) | 2-0 | Atlético Madrid (W) | |
BIIK Kazygurt (W) 1-9 Bayern München (W) *
| 10.03.2021 | Bayern München (W) | 3-0 | BIIK Kazygurt (W) | |
| 04.03.2021 | BIIK Kazygurt (W) | 1-6 | Bayern München (W) | |
*FC Barcelona (W) 9-0 Fortuna Hjorring (W)
| 10.03.2021 | Fortuna Hjorring (W) | 0-5 | FC Barcelona (W) | |
| 03.03.2021 | FC Barcelona (W) | 4-0 | Fortuna Hjorring (W) | |
*Rosengård (W) 4-2 FSK St. Pölten (W)
| 10.03.2021 | FSK St. Pölten (W) | 0-2 | Rosengård (W) | |
| 03.03.2021 | Rosengård (W) | 2-2 | FSK St. Pölten (W) | |
*Wolfsburg (W) 4-0 LSK Kvinner (W)
| 10.03.2021 | LSK Kvinner (W) | 0-2 | Wolfsburg (W) | |
| 03.03.2021 | Wolfsburg (W) | 2-0 | LSK Kvinner (W) | |
*Lyon (W) 5-1 Brøndby (W)
| 10.03.2021 | Brøndby (W) | 1-3 | Lyon (W) | |
| 04.03.2021 | Lyon (W) | 2-0 | Brøndby (W) | |
*Man City (W) 8-0 Fiorentina (W)
| 11.03.2021 | Fiorentina (W) | 0-5 | Man City (W) | |
| 03.03.2021 | Man City (W) | 3-0 | Fiorentina (W) | |
*Paris SG (W) 5-3 Sparta Praha (W)
| 17.03.2021 | Sparta Praha (W) | 3-0 W.O. | Paris SG (W) | |
| 09.03.2021 | Paris SG (W) | 5-0 | Sparta Praha (W) | |