ŽNK Osijek (W) 1-4 Breidablik (W) *
| 09.09.2021 | Breidablik (W) | 3-0 | ŽNK Osijek (W) | |
| 01.09.2021 | ŽNK Osijek (W) | 1-1 | Breidablik (W) | |
*Servette FC Chênois (W) 3-2 Glasgow City (W)
| 08.09.2021 | Glasgow City (W) | 1-2 | Servette FC Chênois (W) | |
| 01.09.2021 | Servette FC Chênois (W) | 1-1 | Glasgow City (W) | |
Sparta Praha (W) 0-3 HB Køge (W) *
| 08.09.2021 | HB Køge (W) | 2-0 | Sparta Praha (W) | |
| 01.09.2021 | Sparta Praha (W) | 0-1 | HB Køge (W) | |
Levante UD (W) 2-4 Lyon (W) *
| 08.09.2021 | Lyon (W) | 2-1 | Levante UD (W) | |
| 01.09.2021 | Levante UD (W) | 1-2 | Lyon (W) | |
*Real Madrid (W) 2-1 Man City (W)
| 08.09.2021 | Man City (W) | 0-1 | Real Madrid (W) | |
| 31.08.2021 | Real Madrid (W) | 1-1 | Man City (W) | |
Rosengård (W) 3-6 Hoffenheim (W) *
| 08.09.2021 | Hoffenheim (W) | 3-3 | Rosengård (W) | |
| 31.08.2021 | Rosengård (W) | 0-3 | Hoffenheim (W) | |
FC Twente (W) 1-5 SL Benfica (W) *
| 09.09.2021 | SL Benfica (W) | 4-0 | FC Twente (W) | |
| 31.08.2021 | FC Twente (W) | 1-1 | SL Benfica (W) | |
*Arsenal LFC (W) 7-0 Slavia Praha (W)
| 09.09.2021 | Slavia Praha (W) | 0-4 | Arsenal LFC (W) | |
| 31.08.2021 | Arsenal LFC (W) | 3-0 | Slavia Praha (W) | |
Valerenga (W) 3-6 BK Hacken FF (W) *
| 08.09.2021 | BK Hacken FF (W) | 3-2 | Valerenga (W) | |
| 01.09.2021 | Valerenga (W) | 1-3 | BK Hacken FF (W) | |
Vllaznia Shkodër (W) 0-3 Juventus (W) *
| 09.09.2021 | Juventus (W) | 1-0 | Vllaznia Shkodër (W) | |
| 01.09.2021 | Vllaznia Shkodër (W) | 0-2 | Juventus (W) | |
*Wolfsburg (W) 5-5 Girondins Bordeaux (W)
| 08.09.2021 | Girondins Bordeaux (W) | 3-2/p.0-3 | Wolfsburg (W) | |
| 01.09.2021 | Wolfsburg (W) | 3-2 | Girondins Bordeaux (W) | |
Apollon Limassol (W) 2-5 Zhytlobud-1 (W) *
| 09.09.2021 | Zhytlobud-1 (W) | 3-1 | Apollon Limassol (W) | |
| 31.08.2021 | Apollon Limassol (W) | 1-2 | Zhytlobud-1 (W) | |