*FK BGU Minsk 3-2 Bumprom Gomel
| 24.10.2020 | Bumprom Gomel | 1-1 | FK BGU Minsk | |
| 17.10.2020 | FK BGU Minsk | 2-1 | Bumprom Gomel | |
Meliorator Zh. 3-5 Dnepr Rogachev *
| 24.10.2020 | Dnepr Rogachev | 3-1 | Meliorator Zh. | |
| 17.10.2020 | Meliorator Zh. | 2-2 | Dnepr Rogachev | |
*Dinamo Brest 1960 7-2 FK Gorki
| 24.10.2020 | FK Gorki | 2-1 | Dinamo Brest 1960 | |
| 17.10.2020 | Dinamo Brest 1960 | 6-0 | FK Gorki | |
Viktoriya Maryina Gorka 4-12 FK Ostrovets *
| 24.10.2020 | FK Ostrovets | 5-0 | Viktoriya Maryina Gorka | |
| 17.10.2020 | Viktoriya Maryina Gorka | 4-7 | FK Ostrovets | |
*FK Chayka Zelva 5-3 FK Zhlobin
| 24.10.2020 | FK Zhlobin | 3-2 | FK Chayka Zelva | |
| 17.10.2020 | FK Chayka Zelva | 3-0 W.O. | FK Zhlobin | |
*Kronon Stolbtsy 4-3 Energetik-BGATU
| 25.10.2020 | Energetik-BGATU | 2-1 | Kronon Stolbtsy | |
| 17.10.2020 | Kronon Stolbtsy | 3-1 | Energetik-BGATU | |
Pershiy Regien 0-6 Polotsk-2019 *
| 24.10.2020 | Polotsk-2019 | 3-0 W.O. | Pershiy Regien | |
| 17.10.2020 | Pershiy Regien | 0-3 W.O. | Polotsk-2019 | |
*FK Ivatsevichi 9-8 SMI Autotrans
| 24.10.2020 | SMI Autotrans | 4-3 | FK Ivatsevichi | |
| 17.10.2020 | FK Ivatsevichi | 6-4 | SMI Autotrans | |