Anderlecht 4-1 FCV Dender EH
| 27.02.2008 | FCV Dender EH | 1-1 | Anderlecht | |
| 30.01.2008 | Anderlecht | 3-0 | FCV Dender EH | |
Cercle Brugge 4-5 Standard Liège
| 27.02.2008 | Standard Liège | 4-0 | Cercle Brugge | |
| 30.01.2008 | Cercle Brugge | 4-1 | Standard Liège | |
Germinal Beerschot 6-2 Roeselare
| 27.02.2008 | Roeselare | 1-1 | Germinal Beerschot | |
| 30.01.2008 | Germinal Beerschot | 5-1 | Roeselare | |
KV Kortrijk 5-5 KAA Gent
| 27.02.2008 | KAA Gent | 4-0 | KV Kortrijk | |
| 30.01.2008 | KV Kortrijk | 5-1 | KAA Gent | |