Bolívar 1-1 The Strongest *
| 17.07.2016 | The Strongest | 0-0/p.3-0 | Bolívar | |
| 10.07.2016 | Bolívar | 1-1 | The Strongest | |
CD San José 5-5 Universitario Sucre *
| 17.07.2016 | Universitario Sucre | 4-2/p.3-1 | CD San José | |
| 10.07.2016 | CD San José | 3-1 | Universitario Sucre | |
*Jorge Wilstermann 2-1 Club Aurora
| 17.07.2016 | Club Aurora | 1-1 | Jorge Wilstermann | |
| 10.07.2016 | Jorge Wilstermann | 1-0 | Club Aurora | |
*Real Potosí 3-2 Nacional Potosí
| 17.07.2016 | Nacional Potosí | 1-2 | Real Potosí | |
| 10.07.2016 | Real Potosí | 1-1 | Nacional Potosí | |
Blooming 0-3 Oriente Petrolero *
| 17.07.2016 | Oriente Petrolero | 1-0 | Blooming | |
| 10.07.2016 | Blooming | 0-2 | Oriente Petrolero | |
Enrique Happ 0-1 Petrolero Yacuiba *
| 17.07.2016 | Petrolero Yacuiba | 1-0 | Enrique Happ | |
| 10.07.2016 | Enrique Happ | 0-0 | Petrolero Yacuiba | |
CD Guabirá 2-5 Sport Boys Warnes *
| 17.07.2016 | Sport Boys Warnes | 2-1 | CD Guabirá | |
| 10.07.2016 | CD Guabirá | 1-3 | Sport Boys Warnes | |