CD Torre Fuerte 3-5 Fancesa *
| 12.12.2020 | Fancesa | 4-2 | CD Torre Fuerte | |
| 09.12.2020 | CD Torre Fuerte | 1-1 | Fancesa | |
Cochabamba FC 1-2 Real Tomayapo *
| 13.12.2020 | Real Tomayapo | 1-0 | Cochabamba FC | |
| 09.12.2020 | Cochabamba FC | 1-1 | Real Tomayapo | |
EM Huanuni 0-1 Independiente Petrolero *
| 13.12.2020 | Independiente Petrolero | 1-0 | EM Huanuni | |
| 09.12.2020 | EM Huanuni | 0-0 | Independiente Petrolero | |
Libertad Beni 0-3 Vaca Díez *
| 13.12.2020 | Vaca Díez | 2-0 | Libertad Beni | |
| 09.12.2020 | Libertad Beni | 0-1 | Vaca Díez | |