*Always Ready 6-2 CDT Real Oruro
| 21.02.2025 | CDT Real Oruro | 1-5 | Always Ready | |
| 18.02.2025 | Always Ready | 1-1 | CDT Real Oruro | |
CD G.V. San José 2-9 Bolívar *
| 22.02.2025 | Bolívar | 7-1 | CD G.V. San José | |
| 16.02.2025 | CD G.V. San José | 1-2 | Bolívar | |
CD San Antonio (BOL) 1-4 Club Aurora *
| 22.02.2025 | Club Aurora | 1-0 | CD San Antonio (BOL) | |
| 14.02.2025 | CD San Antonio (BOL) | 1-3 | Club Aurora | |
*Nacional Potosí 11-3 Independiente Petrolero
| 22.02.2025 | Independiente Petrolero | 0-5 | Nacional Potosí | |
| 16.02.2025 | Nacional Potosí | 6-3 | Independiente Petrolero | |
*Oriente Petrolero 3-3 CD Guabirá
| 23.02.2025 | CD Guabirá | 3-2 | Oriente Petrolero | |
| 17.02.2025 | Oriente Petrolero | 1-0 | CD Guabirá | |
Real Tomayapo 2-3 Jorge Wilstermann *
| 24.02.2025 | Jorge Wilstermann | 2-2 | Real Tomayapo | |
| 15.02.2025 | Real Tomayapo | 0-1 | Jorge Wilstermann | |
*Blooming 3-2 Royal Pari
| 23.02.2025 | Royal Pari | 0-1 | Blooming | |
| 19.02.2025 | Blooming | 2-2 | Royal Pari | |
The Strongest 1-4 Universitario Vinto *
| 20.02.2025 | Universitario Vinto | 3-0 | The Strongest | |
| 15.02.2025 | The Strongest | 1-1 | Universitario Vinto | |