*Celik Zenica 2-1 FK Slavija
| 20.10.2010 | FK Slavija | 0-1 | Celik Zenica | |
| 29.09.2010 | Celik Zenica | 1-1 | FK Slavija | |
Borac Banja Luka 0-3 FK Zeljeznicar *
| 20.10.2010 | FK Zeljeznicar | 3-0 | Borac Banja Luka | |
| 29.09.2010 | Borac Banja Luka | 0-0 | FK Zeljeznicar | |
Leotar Trebinje 1-2 Branitelj Mostar *
| 20.10.2010 | Branitelj Mostar | 1-0 | Leotar Trebinje | |
| 29.09.2010 | Leotar Trebinje | 1-1 | Branitelj Mostar | |
Omladinac Mionica 2-4 Siroki Brijeg *
| 20.10.2010 | Siroki Brijeg | 4-0 | Omladinac Mionica | |
| 29.09.2010 | Omladinac Mionica | 2-0 | Siroki Brijeg | |
*FK Sarajevo 7-2 Sloboda Novi Grad
| 20.10.2010 | Sloboda Novi Grad | 1-3 | FK Sarajevo | |
| 29.09.2010 | FK Sarajevo | 4-1 | Sloboda Novi Grad | |
Kozara Gradiska 3-5 Sloboda Tuzla *
| 20.10.2010 | Sloboda Tuzla | 4-2 | Kozara Gradiska | |
| 29.09.2010 | Kozara Gradiska | 1-1 | Sloboda Tuzla | |
Olimpik Sarajevo 7-2 UNIS Vogošca
| 19.10.2010 | UNIS Vogošca | 1-2 | Olimpik Sarajevo | |
| 30.09.2010 | Olimpik Sarajevo | 5-1 | UNIS Vogošca | |
Proleter Teslić 4-5 Zrinjski Mostar
| 19.10.2010 | Zrinjski Mostar | 3-0 | Proleter Teslić | |
| 28.09.2010 | Proleter Teslić | 4-2 | Zrinjski Mostar | |