Araguaína/TO 6-4 Brasília FC/DF
| 02.10.2010 | Brasília FC/DF | 1-2 | Araguaína/TO | |
| 25.09.2010 | Araguaína/TO | 4-3 | Brasília FC/DF | |
Joinville/SC 1-0 Operário F./PR
| 02.10.2010 | Operário F./PR | 0-1 | Joinville/SC | |
| 26.09.2010 | Joinville/SC | 0-0 | Operário F./PR | |
Uberaba/MG 1-3 Madureira/RJ
| 02.10.2010 | Madureira/RJ | 0-0 | Uberaba/MG | |
| 25.09.2010 | Uberaba/MG | 1-3 | Madureira/RJ | |
Guarany/CE 4-3 Sampaio Correa/MA
| 02.10.2010 | Sampaio Correa/MA | 1-1 | Guarany/CE | |
| 26.09.2010 | Guarany/CE | 3-2 | Sampaio Correa/MA | |
América/AM 1-3 Vila Aurora/MT
| 02.10.2010 | Vila Aurora/MT | 3-0 | América/AM | |
| 26.09.2010 | América/AM | 1-0 | Vila Aurora/MT | |