Athletico/PR U20 3-4 São Paulo/SP U20 *
| 25.10.2021 | São Paulo/SP U20 | 3-2 | Athletico/PR U20 | |
| 18.10.2021 | Athletico/PR U20 | 1-1 | São Paulo/SP U20 | |
Botafogo/RJ U20 0-2 Atlético/MG U20 *
| 22.10.2021 | Atlético/MG U20 | 2-0 | Botafogo/RJ U20 | |
| 17.10.2021 | Botafogo/RJ U20 | 0-0 | Atlético/MG U20 | |
*Internacional/RS U20 5-4 Palmeiras/SP U20
| 24.10.2021 | Palmeiras/SP U20 | 3-3 | Internacional/RS U20 | |
| 18.10.2021 | Internacional/RS U20 | 2-1 | Palmeiras/SP U20 | |
Vasco/RJ U20 2-4 Flamengo/RJ U20 *
| 26.10.2021 | Flamengo/RJ U20 | 3-0 | Vasco/RJ U20 | |
| 20.10.2021 | Vasco/RJ U20 | 2-1 | Flamengo/RJ U20 | |