AD Turrialba 0-2 CS Cartaginés *
| 25.11.2022 | CS Cartaginés | 1-0 | AD Turrialba | |
| 20.11.2022 | AD Turrialba | 0-1 | CS Cartaginés | |
CS Uruguay 0-6 Saprissa *
| 24.11.2022 | Saprissa | 2-0 | CS Uruguay | |
| 20.11.2022 | CS Uruguay | 0-4 | Saprissa | |
Guadalupe FC 2-2 Puntarenas FC *
| 26.11.2022 | Puntarenas FC | 1-1/p.11-10 | Guadalupe FC | |
| 18.11.2022 | Guadalupe FC | 1-1 | Puntarenas FC | |
*LD Alajuelense 3-1 Guanacasteca
| 26.11.2022 | Guanacasteca | 0-1 | LD Alajuelense | |
| 17.11.2022 | LD Alajuelense | 2-1 | Guanacasteca | |
AD Sarchí 1-3 Municipal Grecia *
| 27.11.2022 | Municipal Grecia | 3-1 | AD Sarchí | |
| 16.11.2022 | AD Sarchí | 0-0 | Municipal Grecia | |
*Sporting (CRC) 5-1 Pérez Zeledón
| 23.11.2022 | Pérez Zeledón | 1-4 | Sporting (CRC) | |
| 19.11.2022 | Sporting (CRC) | 1-0 | Pérez Zeledón | |
*CS Herediano 3-0 Santa Ana
| 27.11.2022 | Santa Ana | 0-0 | CS Herediano | |
| 16.11.2022 | CS Herediano | 3-0 | Santa Ana | |
*Santos Guápiles 5-5 AD San Carlos
| 25.11.2022 | AD San Carlos | 4-1/p.2-3 | Santos Guápiles | |
| 20.11.2022 | Santos Guápiles | 4-1 | AD San Carlos | |