*AEK Larnaca 13-1 Onisilos Sotiras*
| 13.04.2022 | Onisilos Sotiras* | 1-5 | AEK Larnaca | |
| 16.03.2022 | AEK Larnaca | 8-0 | Onisilos Sotiras* | |
AEL Limassol 1-1 Omonia Nicosia *
| 13.04.2022 | Omonia Nicosia | 0-0 | AEL Limassol | |
| 16.03.2022 | AEL Limassol | 1-1 | Omonia Nicosia | |
APOEL FC 2-2 Anorthosis FC *
| 06.04.2022 | Anorthosis FC | 1-0 | APOEL FC | |
| 09.03.2022 | APOEL FC | 2-1 | Anorthosis FC | |
*Ethnikos Achnas 5-0 EN Paralimni
| 06.04.2022 | EN Paralimni | 0-4 | Ethnikos Achnas | |
| 09.03.2022 | Ethnikos Achnas | 1-0 | EN Paralimni | |