MFK Frydek-Mistek 0-5 FK Jablonec *
| 03.11.2015 | FK Jablonec | 3-0 | MFK Frydek-Mistek | |
| 20.10.2015 | MFK Frydek-Mistek | 0-2 | FK Jablonec | |
Jihlava 2-3 Sigma Olomouc *
| 11.11.2015 | Sigma Olomouc | 2-2 | Jihlava | |
| 10.10.2015 | Jihlava | 0-1 | Sigma Olomouc | |
MFK Karviná 0-4 Mlada Boleslav *
| 24.11.2015 | Mlada Boleslav | 3-0 | MFK Karviná | |
| 27.10.2015 | MFK Karviná | 0-1 | Mlada Boleslav | |
*Hradec Kralove 5-2 Pribram
| 11.11.2015 | Pribram | 1-5 | Hradec Kralove | |
| 27.10.2015 | Hradec Kralove | 0-1 | Pribram | |
*Slovan Liberec 1-1 FK Zlin
| 03.12.2015 | FK Zlin | 1-0/p.6-7 | Slovan Liberec | |
| 14.11.2015 | Slovan Liberec | 1-0 | FK Zlin | |
FK Pardubice 2-3 Sparta Praha *
| 03.12.2015 | Sparta Praha | 3-1 | FK Pardubice | |
| 17.11.2015 | FK Pardubice | 1-0 | Sparta Praha | |
Usti nad Labem 0-6 Dukla Praha *
| 10.11.2015 | Dukla Praha | 3-0 | Usti nad Labem | |
| 20.10.2015 | Usti nad Labem | 0-3 | Dukla Praha | |
*Viktoria Plzen 3-1 Zbrojovka Brno
| 03.12.2015 | Zbrojovka Brno | 0-1 | Viktoria Plzen | |
| 15.11.2015 | Viktoria Plzen | 2-1 | Zbrojovka Brno | |