*Platense (SLV) 2-1 Alianza FC (SLV)
| 30.10.2022 | Alianza FC (SLV) | 0-1 | Platense (SLV) | |
| 26.10.2022 | Platense (SLV) | 1-1 | Alianza FC (SLV) | |
Atlético Marte 0-1 CD Águila *
| 30.10.2022 | CD Águila | 1-0 | Atlético Marte | |
| 27.10.2022 | Atlético Marte | 0-0 | CD Águila | |
CD Dragon (SLV) 4-5 CD FAS *
| 30.10.2022 | CD FAS | 3-1 | CD Dragon (SLV) | |
| 26.10.2022 | CD Dragon (SLV) | 3-2 | CD FAS | |
Isidro Metapán 1-1 Jocoro FC *
| 30.10.2022 | Jocoro FC | 0-0/p.4-2 | Isidro Metapán | |
| 28.10.2022 | Isidro Metapán | 1-1 | Jocoro FC | |