| 24.08.2022 | |||
| 20:45 | Forest Green | 0-3 | Brighton |
| 20:45 | Leeds United | 3-1 | Barnsley |
| 20:45 | Tranmere Rovers | 1-2 | Newcastle United |
| 20:45 | Wycombe | 1-3 | Bristol City |
| 23.08.2022 | |||
| 20:45 | Barrow AFC | 2-2/p.1-3 | Lincoln City |
| 20:45 | Bolton Wanderers | 1-4 | Aston Villa |
| 20:45 | Bradford City | 1-2 | Blackburn Rovers |
| 20:45 | Cambridge United | 0-3 | Southampton |
| 20:45 | Colchester United | 0-2 | Brentford FC |
| 20:45 | Crawley Town | 2-0 | Fulham |
| 20:45 | Derby County | 1-0 | West Bromwich |
| 20:45 | Fleetwood Town | 0-1 | Everton |
| 20:45 | Gillingham | 0-0/p.6-5 | Exeter City |
| 20:45 | Grimsby Town | 0-3 | Nottingham Forest |
| 20:45 | Newport County | 3-2 | Portsmouth |
| 20:45 | Norwich City | 2-2/p.3-5 | Bournemouth |
| 20:45 | Oxford United | 0-2 | Crystal Palace |
| 20:45 | Rotherham | 0-1 | Morecambe FC |
| 20:45 | Stevenage FC | 1-0 | Peterborough |
| 20:45 | Stockport County | 0-0/p.1-3 | Leicester City |
| 20:45 | Watford FC | 0-2 | Milton Keynes Dons |
| 20:45 | Wolverhampton | 2-1 | Preston NE |
| 20:30 | Sheffield Wed | 3-0 | Rochdale |
| 20:30 | Shrewsbury | 0-1 | Burnley |
| 20:00 | Walsall FC | 0-1 | Charlton Athletic |
Müsabaka tarayιcιsι
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