Son sonuçlar
hepsini göster| 20.01.2022 | |||
| 21:00 | AFC Ajax | 9-0 | Excelsior Maassluis |
| 18:45 | PSV Eindhoven | 2-1 | SC Telstar |
| 19.01.2022 | |||
| 21:00 | FC Twente | 1-2 | AZ Alkmaar |
| 20:00 | NAC Breda | 2-1 | PEC Zwolle |
| 18:45 | FC Groningen | 1-2 | NEC Nijmegen |
| 18.01.2022 | |||
| 21:00 | SC Heerenveen | 0-1 | Go Ahead Eagles |
| 20:00 | Vitesse Arnhem | 2-0 | DVS '33 |
| 18:45 | RKC Waalwijk | 4-2 AET | ADO Den Haag |