*Atalanta Youth 5-3 Brescia Youth
| 24.11.2010 | Brescia Youth | 2-3 | Atalanta Youth | |
| 10.11.2010 | Atalanta Youth | 2-1 | Brescia Youth | |
*Cittadella Youth 5-2 ChievoVerona Youth
| 24.11.2010 | ChievoVerona Youth | 0-2 | Cittadella Youth | |
| 10.11.2010 | Cittadella Youth | 3-2 | ChievoVerona Youth | |
*Fiorentina Youth 6-1 Empoli Youth
| 24.11.2010 | Empoli Youth | 1-3 | Fiorentina Youth | |
| 10.11.2010 | Fiorentina Youth | 3-0 | Empoli Youth | |
*Inter Milan Youth 3-0 Genoa Youth
| 24.11.2010 | Genoa Youth | 0-1 | Inter Milan Youth | |
| 10.11.2010 | Inter Milan Youth | 2-0 | Genoa Youth | |
*AS Roma Youth 2-2 Lazio Youth
| 24.11.2010 | Lazio Youth | 1-2 | AS Roma Youth | |
| 10.11.2010 | AS Roma Youth | 0-1 | Lazio Youth | |
AS Bari Youth 0-3 Palermo Youth *
| 24.11.2010 | Palermo Youth | 2-0 | AS Bari Youth | |
| 10.11.2010 | AS Bari Youth | 0-1 | Palermo Youth | |
Pescara Youth 0-4 AC Milan Youth *
| 24.11.2010 | AC Milan Youth | 2-0 | Pescara Youth | |
| 10.11.2010 | Pescara Youth | 0-2 | AC Milan Youth | |
Torino Youth 2-3 Sampdoria Youth *
| 24.11.2010 | Sampdoria Youth | 0-1 | Torino Youth | |
| 10.11.2010 | Torino Youth | 1-3 | Sampdoria Youth | |