*Empoli Youth 3-1 Bologna FC Youth
| 01.10.2011 | Bologna FC Youth | 0-2 | Empoli Youth | |
| 14.09.2011 | Empoli Youth | 1-1 | Bologna FC Youth | |
*Cagliari Youth 4-3 Brescia Youth
| 01.10.2011 | Brescia Youth | 1-2 | Cagliari Youth | |
| 14.09.2011 | Cagliari Youth | 2-2 | Brescia Youth | |
Cittadella Youth 2-5 Padova Youth *
| 01.10.2011 | Padova Youth | 5-1 | Cittadella Youth | |
| 14.09.2011 | Cittadella Youth | 1-0 | Padova Youth | |
*Palermo Youth 4-3 FC Crotone Youth
| 09.10.2011 | FC Crotone Youth | 0-1 | Palermo Youth | |
| 14.09.2011 | Palermo Youth | 3-3 | FC Crotone Youth | |
*Siena Youth 6-1 Grosseto Youth
| 01.10.2011 | Grosseto Youth | 1-0 | Siena Youth | |
| 14.09.2011 | Siena Youth | 6-0 | Grosseto Youth | |
Ascoli Youth 0-5 Inter Milan Youth *
| 01.10.2011 | Inter Milan Youth | 2-0 | Ascoli Youth | |
| 21.09.2011 | Ascoli Youth | 0-3 | Inter Milan Youth | |
*Juve Stabia Youth 2-1 AS Bari Youth
| 08.10.2011 | AS Bari Youth | 0-2 AET | Juve Stabia Youth | |
| 14.09.2011 | Juve Stabia Youth | 0-1 | AS Bari Youth | |
Reggina Youth 4-3 Lecce Youth *
| 08.10.2011 | Lecce Youth | 2-2 | Reggina Youth | |
| 14.09.2011 | Reggina Youth | 2-1 | Lecce Youth | |
Modena Youth 1-6 Novara Youth *
| 01.10.2011 | Novara Youth | 2-0 | Modena Youth | |
| 14.09.2011 | Modena Youth | 1-4 | Novara Youth | |
*Napoli Youth 3-1 Catania Youth
| 01.10.2011 | Catania Youth | 1-1 | Napoli Youth | |
| 14.09.2011 | Napoli Youth | 2-0 | Catania Youth | |
Cesena Youth 5-6 Pescara Youth *
| 01.10.2011 | Pescara Youth | 5-1 | Cesena Youth | |
| 14.09.2011 | Cesena Youth | 4-1 | Pescara Youth | |
*Parma Youth 4-2 Sampdoria Youth
| 01.10.2011 | Sampdoria Youth | 2-1 | Parma Youth | |
| 14.09.2011 | Parma Youth | 3-0 | Sampdoria Youth | |
*Sassuolo Youth 7-4 Udinese Youth
| 01.10.2011 | Udinese Youth | 1-3 | Sassuolo Youth | |
| 14.09.2011 | Sassuolo Youth | 4-3 | Udinese Youth | |
Livorno Youth 1-5 Torino Youth *
| 01.10.2011 | Torino Youth | 3-1 | Livorno Youth | |
| 14.09.2011 | Livorno Youth | 0-2 | Torino Youth | |
Verona Youth 1-4 ChievoVerona Youth *
| 01.10.2011 | ChievoVerona Youth | 2-1 | Verona Youth | |
| 14.09.2011 | Verona Youth | 0-2 | ChievoVerona Youth | |
Vicenza Youth 1-5 AlbinoLeffe Youth *
| 01.10.2011 | AlbinoLeffe Youth | 4-1 | Vicenza Youth | |
| 14.09.2011 | Vicenza Youth | 0-1 | AlbinoLeffe Youth | |