*AS Bari Youth 4-3 Reggina Youth
| 06.10.2012 | Reggina Youth | 1-2 | AS Bari Youth | |
| 19.09.2012 | AS Bari Youth | 2-2 | Reggina Youth | |
*Udinese Youth 4-2 Ascoli Youth
| 03.10.2012 | Ascoli Youth | 2-2 | Udinese Youth | |
| 19.09.2012 | Udinese Youth | 2-0 | Ascoli Youth | |
Atalanta Youth 3-5 Modena Youth *
| 06.10.2012 | Modena Youth | 2-3 | Atalanta Youth | |
| 15.09.2012 | Atalanta Youth | 0-3 W.O. | Modena Youth | |
Bologna FC Youth 2-5 Parma Youth *
| 03.10.2012 | Parma Youth | 3-0 | Bologna FC Youth | |
| 19.09.2012 | Bologna FC Youth | 2-2 | Parma Youth | |
*Brescia Youth 5-1 Cagliari Youth
| 03.10.2012 | Cagliari Youth | 1-1 | Brescia Youth | |
| 19.09.2012 | Brescia Youth | 4-0 | Cagliari Youth | |
*Catania Youth 4-1 Vicenza Youth
| 03.10.2012 | Vicenza Youth | 1-1 | Catania Youth | |
| 19.09.2012 | Catania Youth | 3-0 | Vicenza Youth | |
Cittadella Youth 4-5 Cesena Youth *
| 06.10.2012 | Cesena Youth | 3-2 | Cittadella Youth | |
| 19.09.2012 | Cittadella Youth | 2-2 | Cesena Youth | |
*ChievoVerona Youth 6-0 Virtus Lanciano Youth
| 03.10.2012 | Virtus Lanciano Youth | 0-3 | ChievoVerona Youth | |
| 19.09.2012 | ChievoVerona Youth | 3-0 | Virtus Lanciano Youth | |
*Empoli Youth 4-3 Genoa Youth
| 03.10.2012 | Genoa Youth | 1-2 | Empoli Youth | |
| 19.09.2012 | Empoli Youth | 2-2 | Genoa Youth | |
*Grosseto Youth 4-3 Pro Vercelli Youth
| 03.10.2012 | Pro Vercelli Youth | 3-1 | Grosseto Youth | |
| 19.09.2012 | Grosseto Youth | 3-0 | Pro Vercelli Youth | |
Juve Stabia Youth 3-5 Pescara Youth *
| 06.10.2012 | Pescara Youth | 4-1 AET | Juve Stabia Youth | |
| 15.09.2012 | Juve Stabia Youth | 2-1 | Pescara Youth | |
*Siena Youth 6-2 Livorno Youth
| 03.10.2012 | Livorno Youth | 0-3 | Siena Youth | |
| 19.09.2012 | Siena Youth | 3-2 | Livorno Youth | |
FC Crotone Youth 2-7 Napoli Youth *
| 03.10.2012 | Napoli Youth | 3-0 | FC Crotone Youth | |
| 19.09.2012 | FC Crotone Youth | 2-4 | Napoli Youth | |
Fiorentina Youth 3-3 Sampdoria Youth
| 24.10.2012 | Sampdoria Youth | 1-1 | Fiorentina Youth | |
| 19.09.2012 | Fiorentina Youth | 2-2 | Sampdoria Youth | |
Sassuolo Youth 3-4 Novara Youth *
| 03.10.2012 | Novara Youth | 1-3 | Sassuolo Youth | |
| 15.09.2012 | Sassuolo Youth | 0-3 W.O. | Novara Youth | |
Verona Youth 2-6 Padova Youth *
| 03.10.2012 | Padova Youth | 3-0 | Verona Youth | |
| 19.09.2012 | Verona Youth | 2-3 | Padova Youth | |