*CF Monterrey 2-1 Tigres UANL
| 12.05.2013 | Tigres UANL | 1-1 | CF Monterrey | |
| 09.05.2013 | CF Monterrey | 1-0 | Tigres UANL | |
*Cruz Azul 4-3 Monarcas Morelia
| 13.05.2013 | Monarcas Morelia | 1-0 | Cruz Azul | |
| 10.05.2013 | Cruz Azul | 4-2 | Monarcas Morelia | |
*Santos Laguna 3-1 Club Atlas
| 13.05.2013 | Club Atlas | 1-3 | Santos Laguna | |
| 10.05.2013 | Santos Laguna | 0-0 | Club Atlas | |
UNAM Pumas 1-3 Club América *
| 12.05.2013 | Club América | 2-1 | UNAM Pumas | |
| 09.05.2013 | UNAM Pumas | 0-1 | Club América | |