Santos Laguna 0-2 CF Monterrey *
| 14.05.2023 | CF Monterrey | 2-0 | Santos Laguna | |
| 11.05.2023 | Santos Laguna | 0-0 | CF Monterrey | |
Atlético San Luis 3-4 Club América *
| 14.05.2023 | Club América | 1-2 | Atlético San Luis | |
| 11.05.2023 | Atlético San Luis | 1-3 | Club América | |
*Tigres UANL 5-4 Deportivo Toluca
| 14.05.2023 | Deportivo Toluca | 3-1 | Tigres UANL | |
| 12.05.2023 | Tigres UANL | 4-1 | Deportivo Toluca | |
Club Atlas 1-1 Guadalajara Chivas *
| 15.05.2023 | Guadalajara Chivas | 1-0 | Club Atlas | |
| 12.05.2023 | Club Atlas | 1-0 | Guadalajara Chivas | |