*AC Juvenes/Dogana 3-2 SP Cailungo
| 19.10.2022 | SP Cailungo | 1-1 | AC Juvenes/Dogana | |
| 05.10.2022 | AC Juvenes/Dogana | 2-1 | SP Cailungo | |
FC Domagnano 2-8 AC Libertas *
| 19.10.2022 | AC Libertas | 6-2 | FC Domagnano | |
| 04.10.2022 | FC Domagnano | 0-2 | AC Libertas | |
FC Fiorentino 1-8 SP La Fiorita *
| 18.10.2022 | SP La Fiorita | 3-1 | FC Fiorentino | |
| 04.10.2022 | FC Fiorentino | 0-5 | SP La Fiorita | |
SS San Giovanni 2-3 Folgore Calcio *
| 18.10.2022 | Folgore Calcio | 3-2 AET | SS San Giovanni | |
| 05.10.2022 | SS San Giovanni | 0-0 | Folgore Calcio | |
SC Faetano 3-5 SS Murata *
| 18.10.2022 | SS Murata | 4-0 | SC Faetano | |
| 05.10.2022 | SC Faetano | 3-1 | SS Murata | |
*SP Tre Penne 4-1 SS Pennarossa
| 19.10.2022 | SS Pennarossa | 1-4 | SP Tre Penne | |
| 05.10.2022 | SP Tre Penne | 0-0 | SS Pennarossa | |