*Bayburt Ozel Idare 2-0 Hekimoğlu Trabzon
| 16.05.2022 | Hekimoğlu Trabzon | 0-2 | Bayburt Ozel Idare | |
| 12.05.2022 | Bayburt Ozel Idare | 0-0 | Hekimoğlu Trabzon | |
Isparta 32 SK 1-4 Karacabey Bld. *
| 16.05.2022 | Karacabey Bld. | 2-1 | Isparta 32 SK | |
| 12.05.2022 | Isparta 32 SK | 0-2 | Karacabey Bld. | |
Sivas Bld. SK 0-1 Bodrumspor SK *
| 16.05.2022 | Bodrumspor SK | 1-0 | Sivas Bld. SK | |
| 12.05.2022 | Sivas Bld. SK | 0-0 | Bodrumspor SK | |
*Tarsus İdman Yurdu 0-0 Amedspor
| 16.05.2022 | Amedspor | 0-0/p.6-7 | Tarsus İdman Yurdu | |
| 12.05.2022 | Tarsus İdman Yurdu | 0-0 | Amedspor | |