Son sonuçlar
hepsini göster| 08.09.2022 | |||
| 23:15 | Colón FC (URU) | 0-2 | CA Peñarol |
| 07.09.2022 | |||
| 23:15 | Miramar Misiones | 0-1 | Nacional (URU) |
| 23:00 | CA Central | 0-2 | Boston River |
| 23:00 | Deportivo Colonia | 0-2 | Cerro Largo |
| 16:45 | Racing Club (URU) | 0-1 | Defensor Sporting |
| 06.09.2022 | |||
| 23:30 | Universitario Salto | 1-3 | Mvo Wanderers |
| 18:00 | Rampla Juniors FC | 2-1 | CD Maldonado |
| 01.09.2022 | |||
| 16:45 | Mar de Fondo FC | 0-1 | CS Cerrito |
| 31.08.2022 | |||
| 23:15 | Central Español FC | 1-2 | Liverpool (URU) |
| 23:00 | Durazno FC | 1-3 | Plaza Colonia |
| 18:15 | CA Progreso | 2-2/p.4-3 | Danubio FC |
| 18:00 | Juventud LP | 0-0/p.4-5 | Albion FC (URU) |